SERPING1 and hereditary angioedema: Serum CRP level was higher during the symptom-free period, compared with that observed in the healthy subjects (median: 2.20 (1.85–3.78) vs. 1.50 (0.85–2.17) mg/l; p = 0.0031), and increased further significantly during attacks (median: 2.20 (1.85–3.78) vs. 3.39 (1.96–4.98) mg/l; p = 0.0321) in the same C1-INH-HAE patients.