CXCL8 and hereditary angioedema: During edematous attacks, however, IL-8 levels were higher than during symptom-free periods [median (25–75 percentile) 2.43(1.95–5.46) vs. 1.69 (0.82–2.71) pg/ml; p = 0.0061] in the same C1-INH-HAE patients.