TNF and metabolic dysfunction-associated steatohepatitis: In terms of liver function, a meta-analysis of four randomized controlled trials, comprising of 134 non-alcoholic fatty liver and non-alcoholic steatohepatitis patients, demonstrated significant improvements in well-recognized clinical markers of liver damage including Alanine Aminotransferase (ALT), Aspartate Transaminase (AST) and Tumor Necrosis Factor Alpha (TNFα) [9].