DDIT3 and diffuse large B-cell lymphoma: A systematic integrative study of high-resolution genotyping arrays and RNA sequencing data of two independent large cohorts of homogenously R-CHOP-treated DLBCL patients identified novel focal and recurrent deletions in the chromatin regulator and transcriptional corepressor gene RCOR1 (encoding CoREST1) that are associated with a novel prognostically significant risk-associated gene expression signature [121].