TRAF3 and diffuse large B-cell lymphoma: Zhang B. et al. demonstrated that biallelic or monoallelic deletions/mutations of TRAF3 occur recurrently in roughly 15 % of ABC-DLBCL and GCB-DLBCL (in similar fractions) and correlate with non-canonical NF-κB activity in ABC-DLBCL cases [27].