Although no previous reports have clarified HRCT findings of anti-MDA-5 antibody-positive CADM-ILD, Tanizawa et al. reported that the most common HRCT pattern in anti-MDA-5 antibody-positive DM-ILD is lower GGO/consolidation (50 %) followed by random GGO (33 %) [22]. This evidence concerns the gene IFIH1 and interstitial lung disease.