ICAM1 and Miyoshi myopathy: The very-late antigen-4 (VLA-4) on MM cells binds to fibronectin in the serum, and the lymphocyte function associated antigen-1 (LFA-1) on MM cells binds to intercellular adhesion molecule-1 (ICAM1) on BMSCs [26], causing MM cells to home in to the BM.