The frequencies of OGG1 Ser326Cys (rs1052133), XRCC1 Arg399Gln (rs25487), XPD Asp312Asn (rs1799793), and ERCC6 Met1097Val (rs2228526) polymorphisms have been recently determined in the bladder cancer (BC) patients as compared with clinically healthy residents of Belarus [21]. The gene discussed is ERCC2; the disease is urinary bladder carcinoma.