ZEB1 and hereditary sensory and autonomic neuropathy: Consistent with previous reports that the transcription factors Snail and ZEB1 play an important role in EMT process [16, 18], we found significant increase of such proteins in the DPCs treated with CIP (Figures 4(b) and 5(e)), and the increase of EMT markers was found to be corresponding to the stem cell-like morphology and aggregative behavior.