There was statistical significance between the result from liver biopsy of liver cirrhosis and the value of age, platelet (103/UL), INR in 0.000, Hemoglobin (g/dL) in 0.024, Total bilirubin (mg/dL) in 0.004, and prothrombin time(%) in 0.008 (p<0.05) (Table-III). The gene discussed is F2; the disease is cirrhosis of liver.