Endothelial-monocyte activating polypeptide II has been recognized as an angiostatic mediator that suppresses neovascularization, induced endothelial cell apoptosis, inhibited tumor vessel formation, and suppressed primary and metastatic tumor growth (Schwarz et al., 1999; Berger et al., 2000). Here, AIMP1 is linked to metastatic neoplasm.