LGALS1 and proliferative vitreoretinopathy: In human specimens, galectin-1 expression co-localized to the migrated RPE cells in fibrous tissues surgically removed from eyes with proliferative vitreoretinopathy, and in vitro stimulation by hepatocyte growth factor caused a migratory RPE phenotype via elevation of galectin-1 levels, mimicking the pathogenesis of proliferative vitreoretinopathy19.