Immunobloting analysis of tumour tissues showed that platycodin D enhanced the expression of FOXO3a, p21, p27, Bax and cleaved PARP, while decreased the expression of MDM2, Bcl‐2, cyclin B1 and D1 and CDK‐1, ‐2, ‐4 and ‐6. The gene discussed is BCL2; the disease is neoplasm.