In previous study, we successfully identified long non-coding RNAs in Smad3 wild-type (WT) and knock-out (KO) mouse models of obstructive nephropathy (UUO) and immunologically-induced anti-glomerular basement membrane glomerulonephritis (anti-GBM GN) by using RNA-seq11, 12. The gene discussed is SMAD3; the disease is glioblastoma.