Of the 18 mRNA targets up-regulated in inflamed large-IECs, 9 (CCL3, TREM1, NCF4, CXCL9, NCF2, SLC11A1, CD97, SFPQ, and CXCL16) were revealed to correlate with results from previous studies of IBD (Table 3)17, 18, 19, 20, 21, 22, 23, 24, 25. This evidence concerns the gene NCF4 and inflammatory bowel disease.