PDCD10 and colorectal carcinoma: Importantly, transient knockdown of PDCD10 eliminated the chemo sensitizing effect of miR‐425‐5p inhibitor, whereas overexpression of PDCD10 recapitulated this effect in HCT116‐R cells (Fig. 5), demonstrating that miR‐425‐5p exerts its function as a regulator of chemoresistance via PDCD10 in these CRC cells.