As shown in Figure 4E, cotransfection of miR‐425‐5p precursor with wild‐type PDCD103′‐UTR reporter construct significantly repressed relative luciferase activity, whereas mutation of the miR‐425‐5p‐binding site eliminated this effect, supporting that PDCD10 is a direct target of miR‐425‐5p in CRC cells. Here, PDCD10 is linked to colorectal carcinoma.