Significant somatic amplifications of NKX2-1, TERT, EGFR, CCND1, MDM2, CDK4, MET, MYC and MECOM were observed, as well as deletion of TP53, PTPRD and CDKN2A/2B that have been widely reported in lung adenocarcinoma. The gene discussed is EGFR; the disease is lung adenocarcinoma.