IQGAP3 and lung adenocarcinoma: Furthermore, Multivariate Cox proportional hazard analysis showed that a higher level of IQGAP3 was an independent risk factor for poor prognosis of the lung adenocarcinoma patients (Supplementary Data 18 and 19, hazard ratio=2.28, 95% confidence interval=1.25–4.14, P=0.007).