GH1 and cardiac hypertrophy: The result is consistent with previous studies showing a cardioprotective effect ofGH on the synthesis of type I and III collagen during pathological cardiacremodeling.20,21 In rats with ventricular hypertrophy induced by chronicpressure overload, GH induced a cardioprotective effect, attenuating myocardialfibrosis.21 However, notanalyzing the collagen type (IαI, IαII and III) was a limitation of ourstudy, because it can vary according to the type of stimulus (physiological orpathological), and with the supplementation of substances and exercise intensity.