60, 61. Elevated expression of N‐Cadherin in IH‐CC was also linked to aggressive behavior with increased metastasis and invasion 62. However, a recent study was able to show that N‐Cadherin expression was significantly lower in metastatic liver PDAC than in CCs, possibly enabling a differentiation of these tumor subtypes in conjunction with other markers 63. This evidence concerns the gene CDH2 and neoplasm.