GABRB3 and infantile epileptic encephalopathy: However, p.Pro11Ser was later described in an asymptomatic individual, suggesting it may be a rare single nucleotide polymorphism.6, 15 Interestingly, genetic variants implicated in childhood absence epilepsy are clustered much closer to the N‐terminal domain of the protein than those identified in GABRB3 early infantile epileptic encephalopathy (Fig. 1a).