MSTN and hydrops fetalis: We sought to determine the gene expression patterns of the same key regulators of fatty acid uptake, oxidation, glucose metabolism and transcriptional regulators in white adipose tissue of WT and Mstn−/− mice subjected to HF diet with a view of developing an understanding of mechanisms underpinning the excessive fat deposits in the Mstn−/− mice fed on high-fat diet (Fig. 8b–d).