The aim of this study was to investigate the profilesof some pro-inflammatory factors, cytokinesand hormones, such as CRP, TNF-α, leptin as wellas resistin, known to be involved in the process ofinflammation, to evaluate their relationship withlipid hydroperoxides, the markers of early lipidperoxidation and to assess their associations withfemale infertility. The gene discussed is TNF; the disease is Infertility.