SNP array identified frequent shared copy number events in all three tumor regions including FGFR1 amplification at chromosome 8p11.23 and classical CDK4, HMGA2 and MDM2 amplification at chromosome 12q13-15 region and deletion of TP53BP1 at chromosome 15q15 (Figure 6A). The gene discussed is TP53BP1; the disease is neoplasm.