When the AFB+TB and AFB−TB subjects were combined to compare with LTBI or HC, the results were in similar range (for the CD8+CD161+ index, AUC = 0.8444 [95% CI 0.7932–0.8949] or 0.8821[95% CI 0.8485–0.9157] , sensitivity = 0.7740 [95% CI 0.7111–0.8290] or 0.7115 [95% CI 0.6448–0.7721], specificity = 0.8571 [95% CI 0.7637–0.9239] or 0.9050 [95% CI 0.8523–0.9437], and odds ratio = 5.42 or 7.49). Here, KLRB1 is linked to tuberculosis.