Since little work has been reported on ITPKB function in lung cancer pathogenesis, further studies in vitro and in vivo are needed to explore the potential effect of ITPKB in lung cancer, which will be helpful for understanding the role of miR-375 in lung cancer and if miR-375 upregulation is a cause or effect of cancer pathogenesis. Here, ITPKB is linked to lung carcinoma.