INS and Hyperglycemia: Hyperglycemia was reported in eight studies including 1619 patients.[13, 16, 30, 32–36] The reported proportion of patients requiring insulin therapy was 15.4% (127/825) among patients treated with adjunctive corticotherapy versus 8.2% (65/794) among patients treated with antimicrobial therapy alone (RR 1.59; 95% CI 1.06 to 2.38, p = 0.025).