In addition, the cytokine profile after administration of vaccine showed that healthy controls had significantly greater levels of fractalkine, IFN-γ, MCP-3, interleukin 1β, interleukin 6, and MIP-1α [36] i.e. they had a higher inflammatory cytokine load that might have influence on microglial activation and delirium days [37]. The gene discussed is IFNG; the disease is delirium.