Similarly, previous results from our laboratory have shown that MCP-1α, MIP-1α, RANTES, IFN-γ, and IL-8 were increased upon RSV-infection in neonatal lambs on day 6 [1], whereas the anti-inflammatory mediator, IL-10, was down regulated at day 6 post-infection, but increased on day 3 post-infection [28]. The gene discussed is CXCL8; the disease is infection.