CD4 and diabetes mellitus: In multivariable analysis, male gender, HCV-Ab positive status independently from HCV RNA results, a higher baseline HIV RNA, a previous diagnosis of diabetes and daily alcohol intake were all independently predictive of a FIB-4 index >1.45, while MSM as compared to heterosexual contacts and those with higher pre-ART CD4 counts had lower odds of showing an altered FIB-4 at cART initiation.