By this mechanism, MV induces ICD in human melanoma.50 Following ICD of cancer cells infected with MV vaccine, the apoptotic bodies are ingested by DCs, which mature and then produce high levels of IFN-α, and cross-present TAAs, leading to a generation of tumor-specific CD8+ cytotoxic T cells.51,52. The gene discussed is CD8A; the disease is neoplasm.