CEACAM5 and medullary thyroid gland carcinoma: Two phase I clinical trials assessing anti-CEA × anti-diethylene-triamine-pentaacetic acid (DTPA)-indium BsmAb (murine F6 × 734 and chimeric hMN14 × 734 BsmAb) with 131I-labeled di-DTPA-indium hapten showed encouraging therapeutic results in patients with progressive metastatic MTC, with a significantly improved overall survival for intermediate- and high-risk patients (11).