The authors conclude that their results indicate that SOX11-negative MCL may be a particular subtype of this tumor characterized by more frequent morphological and immunophenotypic terminal B cell differentiation features that may be facilitated by the absence of SOX11 transcription factor; however, more molecular and clinical data are needed to reject the hypothesis that the findings are just a minor aberration from the general, something very common in all kinds of cancer. Here, SOX11 is linked to mantle cell lymphoma.