GPX2 and Familial prostate cancer: In A549 cells, we could additionally monitor the expression levels of Gpx2, a selenoprotein upregulated by Nrf2 during oxidative stress (Brigelius-Flohé et al., 2012) and overexpressed in colorectal and prostate cancer (Emmink et al., 2014, Naiki et al., 2014).