BRF2 and breast carcinoma: Since Brf2 has been recently discovered as a top-scoring candidate driver in breast carcinomas (Sanchez-Garcia et al., 2014), we additionally investigated the effects of Brf2 overexpression on selenoproteins expression levels and evasion of apoptosis in MCF10A cells, a mammary epithelium cell line with low expression of Brf2.