To identify putative differential expression patterns according to glioblastoma location, VEGFC, FLT4, MET, HGF, CHI3L1, PROM1, NOTCH1, DLL3, PDGFRA, and BCAN RNA expression levels were compared between cortical (n = 24) and periventricular tumor samples (n = 35). This evidence concerns the gene NOTCH1 and neoplasm.