EZH2 and neoplasm: It is expected that tumor types in which EZH2 gain-of-function mutations occur (e.g., DLBCL and FL) (Campbell et al. 2015) as well as tumors harboring mutations in SWI/SNF components (Wilson et al. 2010; Knutson et al. 2013; Bitler et al. 2015) might benefit from these molecules.