The average levels of serum IL-2, IFN-γ, IL-10, IL-4 and IL-12 in the PC group compared with the control group were 50.632 ± 6.29 pg/mL v. s. 66.973 ± 6.80 pg/mL, 15.140 ± 1.95 pg/mL v. s. 63.880 ± 5.84 pg/mL, 12.276 ± 2.00 pg/mL v. s. 13.297 ± 1.640 pg/mL, 7.614 ± 0.87 pg/mL v. s. 7.851 ± 1.15 pg/mL and 4.621 ± 0.46 pg/mL v. s. 5.084 ± 0.50 pg/mL, respectively. Here, IFNG is linked to pachyonychia congenita.