HIF1A and ovarian cancer: Rg3 inhibits the proliferation of colorectal cancer by inhibiting the Wnt/Δ-catenin pathway [14], promotes apoptosis of ovarian cancer cells by inhibiting the PI3K/AKT pathway [15], inhibits angiogenesis of esophageal cancer induced by oxygen deficit [16], and inhibits EMT in ovarian cancer by reducing HIF-1α [17].