Conversely, there was a 23% reduction in aggressive PCa among men who possessed at least one minor NAT2 rs4646247 A allele when compared to those with the reference genotype [OR (95%CI) = 0.77 (0.60–0.98); p = 0.044, FDR = 0.405]. The gene discussed is NAT2; the disease is posterior cortical atrophy.