In the case of PD, the main genes which are epigenetically regulated through methylation are SNCA, PARK6, CYP2E1, PINK1, BDNF, FGF, MAPT, MTHFR, OLFR 151, PARK16, PARK2, PARK7, TPPP, PDE4D, and METRNL. This evidence concerns the gene PARK7 and Parkinson disease.