TGF-β is the only factor described as participating in the four events of EMT and two molecules: hepatocytes growth factor (HGF) (41) and bone morphogenic protein-7 (BMP-7) (42) have been demonstrated as being capable of reversing the process of EMT due to inhibition of TGF-β and hence decreasing renal fibrosis. The gene discussed is TGFB1; the disease is renal fibrosis.