LAMB2 and paracoccidioidomycosis: González et al. (2008b) evaluated Paracoccidioides conidia treated with laminin, fibronectin, and fibrinogen in mice experimental PCM. They observed that the treatment with all ECM proteins, especially laminin and fibrinogen, induces a less severe pathology, with a decrease of chitin content in the lungs. In a different study, André et al. (2004) treated yeasts of Paracoccidioides with laminin and they to observed that this treatment induces a less severe pathology.