CXCL8 and breast cancer: Comparing this KEGG analysis with a similar IPA signaling analysis (Figure 6C), we again found that multiple pathways, linked again to cytoskeletal activity (breast cancer regulation by Stathmin 1, rac signaling, and actin cytoskeleton signaling) and also receptor platform signaling (IL-8 signaling and ephrin B signaling) were significantly populated by both datasets (transcriptomic and proteomic).