SIX2 and neoplasm: Other verified mutations identified include somatic single nucleotide variants (SNVs) or small deletions in WT1 (three patients, 4.5%), CTNNB1 (five patients, 6.5%), WTX (also known as FAM123B or AMER1, five patients, 6.5%), DROSHA (seven patients, 10%), DGCR8 (three patients, 4.5%), and SIX1 or SIX2 (eight tumours, 10%)6.