PRKACB and liver cancer: Highly upregulated in liver cancer (HULC) inhibits miR-372 activity in an autoregulatory loop that reduces translational repression of its target gene, protein kinase A catalytic subunit beta (PRKACB), and in turn inducing the phosphorylation of camp response element-binding protein (CREB), a transcriptional factor that regulates HULC expression [19].