We identified 16 candidate genes, including the gamma-aminobutyric acid receptor pi (GABRP), epithelial stromal interaction 1 (EPSTI1), bone morphogenetic protein 6 (BMP6), integrin beta 5 (ITGB5), spectrin repeat containing nuclear envelope 1 (SYNE1), and TIMP metallopeptidase inhibitor 3 (TIMP3), from SLE (Our not published data). The gene discussed is SYNE1; the disease is systemic lupus erythematosus.