However, in contrast to the findings that ABCG2 C421A A allele conferred an increased risk of BC and DLBCL, Korenaga et al. found that ABCG2 C421A CC genotype was associated with a higher risk for developing nonpapillary renal cell carcinoma [18]. This evidence concerns the gene ABCG2 and hereditary clear cell renal cell carcinoma.