In the TCGA datasets ADAMTS19 was frequently hypermethylated in gastrointestinal cancers including stomach (47.6–53.7 %), esophageal (39.8 %), liver (30.9 %), colorectal (22.2–25.2 %), and pancreatic cancers (13.8 %). This evidence concerns the gene ADAMTS19 and pancreatic neoplasm.