Previously, the prognostic importance of score A was documented by a candidate gene (total of 12 genes) approach in patients with stable coronary artery disease that were approximately 10 years younger than our patient population and had a 5-year mortality <10%, while score B was derived from a genome-wide association study of patients of around 40 years of age with hypertension that examined effects on plasma ACE activity [10, 11]. The gene discussed is ACE; the disease is Hypertension.