ESS2 and neoplasm: Previous work by Schroder et al. demonstrated the possibility of tumor cell purging in the setting of a suspension of ovarian tissue, where epithelial tumor cell lysis was achieved by cytotoxic T cell retargeting through the bispecific antibody BIS-1, with combined affinity for the T-cell receptor and epithelial glycoprotein-2 (EGP-2)65.