BMI1 was detected being rapidly recruited to DNA lesions caused by local micro-irradiation using UV laser beam, ionizing irradiation (IR), and hydroxyurea (HU) in a set of cell types, including U2OS, mouse embryonic fibroblasts (MEFs), HeLa, and CD133+ glioblastoma multiforme (GBM) cells [74,75,76,77,78]. The gene discussed is BMI1; the disease is glioblastoma.