PON1 and hepatocellular carcinoma: The current study was conducted to investigate the association between 2 SNPs (rs662, rs705382) of the PON1 gene, and CHB, LC, and HCC risks in a substantial number of cases and controls (99 CHB patients, 84 LC, 258 HCC, and 221 healthy controls), which greatly increased statistical power of the study when compared with previous studies.