To date, only 1 hospital-based case-control study has investigated the association of PON1 rs662 polymorphism with HCC susceptibility.26 Another common polymorphism of PON1 is the rs705382 SNP, which is a C/G substitution at codon 1434 of the 5’-untranslated region (UTR). The gene discussed is PON1; the disease is hepatocellular carcinoma.