Given the above GSEA results and our DICER1 expression and genotype findings, which were replicated in three independent cohorts as described in the subsequent sections, we aimed to obtain more evidence towards our hypothesis that the DICER1 and the miRNA pathway is involved in molecular mechanisms of PTSD&Dep by measuring blood miRNA levels in PTSD&Dep cases and controls. The gene discussed is DICER1; the disease is post-traumatic stress disorder.